Highly Purified Chorionic Gonadotrophin Injection HUCOG 10000 Highly Purified Chorionic Gonadotrophin Injection HUCOG\u00ae 2000 HP \/ 5000 HP \/ 10000 HP For Subcutaneous \/ Intramuscular Injection only Composition : Each ml contains : Chorionic Gonadotrophin highly purified I.H 2000 I.U. \/ 5000 I.U. \/ 10000 I.U. Water for Injection I.P q.s. Excipients &Stabilizers : Disodium Hydrogen Phosphate Dihydrate I.P., Benzyl […]<\/p>\n","protected":false},"featured_media":580,"comment_status":"open","ping_status":"closed","template":"","meta":{"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false},"product_cat":[8],"product_tag":[],"aioseo_notices":[],"uagb_featured_image_src":{"full":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",900,900,false],"thumbnail":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU-150x150.jpg",150,150,true],"medium":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU-300x300.jpg",300,300,true],"medium_large":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU-768x768.jpg",640,640,true],"large":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",640,640,false],"1536x1536":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",900,900,false],"2048x2048":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",900,900,false],"vw-ecommerce-store-homepage-thumb":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",145,145,false],"easy_testimonial_thumb":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",50,50,false],"woocommerce_thumbnail":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU-300x300.jpg",300,300,true],"woocommerce_single":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU-600x600.jpg",600,600,true],"woocommerce_gallery_thumbnail":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU-100x100.jpg",100,100,true],"zrdn_recipe_image_main":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",600,600,false],"zrdn_recipe_image_json_1x1":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",900,900,false],"zrdn_recipe_image_json_4x3":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",900,900,false],"zrdn_recipe_image_json_16x9":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",900,900,false],"zrdn_recipe_image_json_1x1_s":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",250,250,false],"zrdn_recipe_image_json_4x3_s":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",164,164,false],"zrdn_recipe_image_json_16x9_s":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",200,200,false],"zrdn_custom_print_image":["https:\/\/topresearchchems.com\/wp-content\/uploads\/2017\/01\/HUCOG-\u2013-10000-IU.jpg",40,40,false]},"uagb_author_info":{"display_name":"TOP RESEARCH CHEMS","author_link":"https:\/\/topresearchchems.com\/author\/"},"uagb_comment_info":0,"uagb_excerpt":"HUCOG 10000 Highly Purified Chorionic Gonadotrophin Injection HUCOG\u00ae 2000 HP \/ 5000 HP \/ 10000 HP For Subcutaneous \/ Intramuscular Injection only Composition : Each ml contains : Chorionic Gonadotrophin highly purified I.H 2000 I.U. \/ 5000 I.U. \/ 10000 I.U. Water for Injection I.P q.s. Excipients &Stabilizers : Disodium Hydrogen Phosphate Dihydrate I.P., Benzyl…","_links":{"self":[{"href":"https:\/\/topresearchchems.com\/wp-json\/wp\/v2\/product\/312"}],"collection":[{"href":"https:\/\/topresearchchems.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/topresearchchems.com\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/topresearchchems.com\/wp-json\/wp\/v2\/comments?post=312"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/topresearchchems.com\/wp-json\/wp\/v2\/media\/580"}],"wp:attachment":[{"href":"https:\/\/topresearchchems.com\/wp-json\/wp\/v2\/media?parent=312"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/topresearchchems.com\/wp-json\/wp\/v2\/product_cat?post=312"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/topresearchchems.com\/wp-json\/wp\/v2\/product_tag?post=312"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nHUCOG\u00ae
\n2000 HP \/ 5000 HP \/ 10000 HP
\nFor Subcutaneous \/ Intramuscular Injection only
\nComposition :
\nEach ml contains :
\nChorionic Gonadotrophin highly purified I.H
\n2000 I.U. \/ 5000 I.U. \/ 10000 I.U.
\nWater for Injection I.P
\nq.s.
\nExcipients &Stabilizers :
\nDisodium Hydrogen Phosphate Dihydrate I.P., Benzyl Alcohol I.P., Sucrose I.P., Poloxamer
\n188
\nU.S.P.\/NF, Methionine B.P., Phosphoric acid I.P.
\nOne IU of Chorionic Gonadotrophin is defined as the activity contained in 1.279 mg of the 2nd International
\nStandard Preparation.
\nProperties :
\nChorionic Gonadotrophin (HCG) is a hormonal substance obtained from urine of pregnant women. Its
\naction is predominantly luteinizing.
\nIndications :
\nAnovulatoryinfertility :
\nIn the female, HUCOG HP is used in the treatment of anovulatory infertility. where its administration would
\nform part of recognized treatment regimen involving prior stimulation of follicular maturation and
\nendometrial proliferation e.q. with Menotropin Injection (HUMOG HP).
\nHypogonadotrophin hypogonadism and cryptorchidism :
\nIn the male, HUCOG HP stimulates the interstitial cells of the testes and consequently the secretion of
\nandrogens and the development of secondary sexual characteristics. With concomitant Menotropin
\nInjection therapy, HUCOG HP stimulates the induction and maintenance of spermatogenesis.
\nDosage and Administration :
\nHUCOG HP is given by subcutaneous \/ intramuscular injection only.
\nAnovulatoryinfertility :
\nHUCOG HP 10000 I.U. is administered in mid-cycle, following treatment with Menotropin Inj. (HUMOG HP)
\naccording to a recognised scheme. Details of Menotropin Inj. (HUMOG HP<\/a>) dosage and monitoring are
\navailable on request.
\nHypogonadotrophichypogonadism :
\nHUCOG HP 2000 I.U. twice weekly concomitant with Menotropin Inj. (HUMOG HP) (1 vial three times a
\nweek) if necessary for a minimum period of four months.
\nCryptorchidism :
\nEquivalent to 1000 I.U. of HUCOG HP on alternate days for several weeks.
\nContra-Indication and Warnings :
\nStimulation of ovulation with HUCOG HP may lead to superovulation and the hyperstimulation syndrome.
\nOestrogen assays will detect the excessive response so that HUCOG HP (HCG) may be withheld in that
\nparticular treatment cycle. In the male, high dosages of HUCOG HP may lead to oedema and in such
\ncases dosages should be considerably reduced.
\nIf signs of sexual precocity are observed a reduced dosage regimen should be instituted.
\nSide Effects :
\nHeadache, irritability, restlessness, depression, fatigue, edema, gynecomastia, sexual precocity, pain at
\nthe site of injection.
\nAdverse Events :
\nThe adverse reactions for use in infertility are: (1) Ovarian hyperstimulation (OHSS), a syndrome of
\nsudden ovarian enlargement, ascites with or without pain, and\/or pleural effusion, (2) Rupture of ovarian
\ncysts with resultant hemoperitoneum, (3) Multiple births, and (4) Arterial thrombo-embolism.
\nPRECAUTION :
\nHCG should be used in conjunction with human menopausal gonadotropins only by physicians
\nexperienced with infertility problems who are familiar with the criteria for patient selection,
\ncontraindications, warnings, precautions, and adverse reactions described in the package insert for
\nmenotropins.
\nInteraction with other medicinal products and other forms of interaction :
\nConcomitant use of HuCoG Injection with other agents used to stimulate ovulation
\n(e.g. HMG,
\nclomiphen<\/a>e citrate) may potentiate the follicular response. (See Warnings Precaution &Overdosage.)
\nOverdose :
\nThe effects of an overdose of HuCoG Injection are unknown, nevertheless one could expect ovarian
\nhyperstimulation syndrome (OHSS) to occur, which is further described as below:
\nOvarian Hyperstimulation Syndrome (OHSS) : (See Warnings) :
\nOHSS is a medical event distinct from uncomplicated ovarian enlargement. OHSS is a syndrome that can
\nmanifest itself with increasing degrees of severity. It comprises marked ovarian enlargement, high serum
\nsex steroids, and an increase in vascular permeability which can result in an accumulation of fluid in the
\nperitoneal, pleural and, rarely, in the pericardial cavities.
\nThe following symptomatology may be observed in severe cases of OHSS : abdominal pain,
\nabdominal distension, severe ovarian enlargement, weight gain, dyspnoea, oliguria and gastrointestinal
\nsymptoms including nausea, vomiting and diarrhoea.
\nAdherence to recommended HuCoG Injection dosage, regimen of administration and careful monitoring
\nof therapy will minimize the incidence of ovarian hyper stimulation and multiple gestations. In ART,
\naspiration of all follicles prior to ovulation may reduce the occurrence of hyper stimulation. OHSS may be
\nmore severe and more protracted if pregnancy occurs. Most often, OHSS occurs after hormonal treatment
\nhas been discontinued and reaches its maximum at about seven to ten days following treatment. Usually,
\nOHSS resolves spontaneously with the onset of menses. If severe OHSS occurs, gonadotrophin treatment
\nshould be stopped if still ongoing, the patient hospitalized and specific therapy for OHSS started. This
\nsyndrome occurs with higher incidence in patients with polycystic ovarian disease.
\nOvarian response should be carefully monitored to minimize the risk of overstimulation. If the ovaries are
\nabnormally enlarged on last day of gonadotrophin therapy, HCG should not to be administered in this
\ncourse therapy. This reduces development of OHSS (Ovarian Hyperstimulation Syndrome). Use of
\nultrasound monitoring of ovarian response and\/or measurement of serum estradiol levels can further
\nminimize the risk of overstimulation.
\nStorage :
\nVials of HUCOG HP should be stored between 20C \u2013 80C. Do not freeze. Protect from light. Any unused
\nportion should be discarded.
\nPresentation :
\nHUCOG HP is supplied in vials containing sterile having activity of 2000 I.U. \/ 5000 I.U. \/ 10000 I.U.
\nManufactured in India by :
\nBHARAT SERUMS AND VACCINES LIMITED
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